二氢小檗碱

植物来源:二氢小檗碱(Dihydroberberine)是小檗科植物的主要成分小檗碱(Berberine)的氢化衍生物,属于异喹啉类生物碱

产品:MetaboBerin

规格:98% 二氢小檗碱(HPLC)

功效:降血糖作用、体重管理及其他相关作用

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  • [1] Xu LJ, Lu F, Wei SC, et al. Comparative study of 8-hydroxydihydroberberine and berberine hydrochloride in  the treatment of type 2 diabetes mellitus in rats[J]. Journal of Integrative Medicine, 2009, 1(04): 173-176.

    [2] Turner N, Li JY, Gosby A, et al. Berberine and its more biologically available derivative, dihydroberberine,  inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action[J]. Diabetes, 2008, 57(5): 1414-8.

    [3] Dai B, Ma Y, Wang W, et al. Dihydroberberine exhibits synergistic effects with sunitinib on NSCLC NCI-H460  cells by repressing MAP kinase pathways and inflammatory mediators[J]. J Cell Mol Med, 2017, 21(10):  2573-2585. 

    [4] Li C, Dong N, Wu B, et al. Dihydroberberine, an isoquinoline alkaloid, exhibits protective effect against dextran sulfate sodium-induced ulcerative colitis in mice[J]. Phytomedicine, 2021, 90: 153631. 

    [5] Chen J, Cao J, Fang L, et al. Berberine derivatives reduce atherosclerotic plaque size and vulnerability in  apoE(-/-) mice[J]. J Transl Med, 2014, 12: 326. 

    [6] Xu L, Lin G, Yu Q, et al. Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium  Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice[J]. Front Pharmacol, 2021, 12: 645879.